Research papers of the week – July 22, 2024

Natalia Trochanowska-Pauk; Tomasz Walski; Raghvendra Bohara; Julia Mikolas; Krystian Kubica

International Journal of Molecular Sciences

Ministerial score = 140.0
Journal Impact Factor (2023) = 4.9 (Q1)

Platelet transfusions are routine procedures in clinical treatment aimed at preventing bleeding in critically ill patients, including those with cancer, undergoing surgery, or experiencing trauma. However, platelets are susceptible blood cells that require specific storage conditions. The availability of platelet concentrates is limited to five days due to various factors, including the risk of bacterial contamination and the occurrence of physical and functional changes known as platelet storage lesions. In this article, the problems related to platelet storage lesions are categorized into four groups depending on research areas: storage conditions, additive solutions, new testing methods for platelets (proteomic and metabolomic analysis), and extensive data modeling of platelet production (mathematical modeling, statistical analysis, and artificial intelligence). This article provides extensive information on the challenges, potential improvements, and novel perspectives regarding platelet storage.

DOI:10.3390/ijms25147779

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