Research papers of the week – August 29, 2022

Krzysztof Skowron, Anna Budzyńska, Natalia Wiktorczyk-Kapischke, Karolina Chomacka, Katarzyna Grudlewska-Buda, Monika Wilk, Ewa Wałecka-Zacharska, Małgorzata Andrzejewska, Eugenia  Gospodarek-Komkowska

International Journal of Molecular Sciences

Ministerial score = 140.0
Journal Impact Factor (2022) = 6.208 (Q1)

Stress and anxiety are common phenomena that contribute to many nervous system dysfunctions. More and more research has been focusing on the importance of the gut–brain axis in the course and treatment of many diseases, including nervous system disorders. This review aims to present current knowledge on the influence of psychobiotics on the gut–brain axis based on selected diseases, i.e., Alzheimer’s disease, Parkinson’s disease, depression, and autism spectrum disorders. Analyses of the available research results have shown that selected probiotic bacteria affect the gut–brain axis in healthy people and people with selected diseases. Furthermore, supplementation with probiotic bacteria can decrease depressive symptoms. There is no doubt that proper supplementation improves the well-being of patients. Therefore, it can be concluded that the intestinal microbiota play a relevant role in disorders of the nervous system. The microbiota–gut–brain axis may represent a new target in the prevention and treatment of neuropsychiatric disorders. However, this topic needs more research. Such research could help find effective treatments via the modulation of the intestinal microbiome.

DOI:10.3390/ijms23147820

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