Research papers of the week – December 27, 2021

Piotr Kuropka, Maciej Dobrzyński, Barbara Bażanów, Dominika Stygar, Tomasz Gębarowski, Anna Leśków, Małgorzata Tarnowska, Katarzyna Szyszka, Małgorzata Małecka, Nicole Nowak, Wiesław Stręk, Rafał J. Wiglusz

Materials

Ministerial score = 140.0
JIF Impact Factor (2020) = 3.623(Q1)

Graphene has been one of the most tested materials since its discovery in 2004. It is known for its special properties, such as electrical conductivity, elasticity and flexibility, antimicrobial effect,and high biocompatibility with many mammal cells. In medicine, the antibacterial, antiviral, and antitumor properties of graphene have been tested as intensively as its drug carrying ability. In this study, the protective effect of graphene oxide against Rubella virus infection of human lung epithelial carcinoma cells and human chondrocyte cells was examined. Cells were incubated with graphene oxide alone and in combination with the Rubella virus. The cytopathic effect in two incubation time periods was measured using DAPI dye as a percentage value of the changed cells. It was shown that the graphene oxide alone has no cytopathic effect on any of tested cell lines, while the Rubella virus alone is highly cytopathic to the cells. However, in combination with the graphene oxide percentage of the changed cells, its cytotopathicity is significantly lower. Moreover, it can be concluded that graphene oxide has protective properties against the Rubella virus infection to cells, lowering its cytopathic changes to the human cells.

DOI:10.3390/ma14247788

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