Research papers of the week – June 24, 2024

Katarzyna Sidorczuk; Michał Burdukiewicz; Klara Cerk; Joachim Fritscher; Robert A. Kingsley; Peter Schierack; Falk Hildebrand; Rafał Kolenda

BMC Genomics

Ministerial score = 140.0
Journal Impact Factor (2023) = 3.5 (Q2)

Adhesins are crucial factors in the virulence of bacterial pathogens such as Escherichia coli. However, to date no resources have been dedicated to the detailed analysis of E. coli adhesins. Here, we provide adhesiomeR software that enables characterization of the complete adhesin repertoire, termed the adhesiome. AdhesiomeR incorporates the most comprehensive database of E. coli adhesins and facilitates an extensive analysis of adhesiome. We demonstrate that adhesiomeR achieves 98% accuracy when compared with experimental analyses. Based on analysis of 15,000 E. coli genomes, we define novel adhesiome profiles and clusters, providing a nomenclature for a unified comparison of E. coli adhesiomes.

DOI:10.1186/s12864-024-10525-6

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