Review: Bovine foetal mortality – risk factors, causes, immune responses and immuno-prophylaxis
J. F. Mee; C. Hayes; Tadeusz Stefaniak; Paulina Jawor
Animal
Ministerial score = 200.0
Journal Impact Factor (2023) = 3.6 (Q1)
This review of bovine foetal mortality (>42 d gestation) concluded that while the majority of risk factors associated with sporadic loss operate at animal-level, e.g. foetal plurality, those that operate at herd-level, e.g. some foetopathogenic infections, are more likely to result in abortion outbreaks. While the causes of foetal mortality have traditionally been classified as infectious and non-infectious, in fact, the latter category is a diagnosis of exclusion, generally without determination of the non-infectious cause. This review has also established that the traditional dichotomisation of infectious agents into primary and secondary pathogens is based on a flawed premise and these terms should be discontinued. The delicate balance of the maternal gestational immune system between not rejecting the allograft (conceptus) but rejecting (attacking) foetopathogens is stage-of-pregnancy-dependent thus the timing of infection determines the clinical outcome which may result in persistent infection or foetal mortality. Utilisation of our knowledge of the materno-foetal immune responses to foetopathogenic infection has resulted in the development of numerous mono- and polyvalent vaccines for metaphylactic or prophylactic control of bovine foetal mortality. While some of these have been shown to significantly contribute to reducing the risk of both infection and foetal mortality, others have insufficient, or conflicting evidence, on efficacy. However, recent developments in vaccinology, in particular the development of subunit vaccines and those that stimulate local genital tract immunity, show greater promise.
DOI:10.1016/j.animal.2023.100774
- News
- University
- About university
- Authorities
- Structure
- Campus map
- 70 years of UPWr
- Sustainable Development Goals
- Employee Code of Ethics
- International Relations Office
- Library
- 2024 election
- University events
- Students
- Academic calendar for students
- The study regulations
- Accommodation
- Accident Insurance
- Student guide
- Erasmus+
- Student activities
- Young Minds Project
- Study Abroad
- Centre for Foreign Languages, Humanities and Social Sciences
- CEEPUS
- Library
- UPWr Summer School
- Support for Ukrainian and Belarusian students of UPWr
- Research
- Leading scientific disciplines
- Leading Research Groups
- AgrEn – Agriculture-Environment-Natural Resources
- ASc4Future – Animal Science for Future
- BioActiv – Biocatalysis and biological activity
- BioDivRO – Biodiversity and sustainable development in Agriculture and Horticulture
- BioTech@Life – Biotechnology for life and industry
- DroPOWER – Poultry – from stable to table
- Food&Health – Food and Health
- Inno-WET – Innovative diagnostics and veterinary therapy
- Inoter – Smart and modern technologies in agriculture
- LandArch – Landscape architecture
- OncoVet - Veterinary Oncology
- Plants4FOOD – Plants Processing & Technology for Bioactive Food
- SCR – Sustainable Cities and Regions
- SPACEOS– Space And Close Earth Observation Sciences
- THETA – The Biostatistic Group
- WBVG – Waste and Biomass Valorization Group
- WCE – Water-Climate-Environment
- Research projects
- UPWr Base of Knowledge
- Research papers of the week
- Research papers of the week – May 6, 2024
- Research papers of the week – April 29, 2024
- Research papers of the week – April 22, 2024
- Research papers of the week – April 15, 2024
- Research papers of the week – April 8, 2024
- Research papers of the week – April 1, 2024
- Research papers of the week – March 25, 2024
- Research papers of the week – March 18, 2024
- Research papers of the week – March 11, 2024
- Research papers of the week – March 4, 2024
- Research papers of the week – February 26, 2024
- Research papers of the week – February 19, 2024
- Research papers of the week – February 12, 2024
- Research papers of the week – February 5, 2024
- Research papers of the week – January 29, 2024
- Research papers of the week – January 22, 2024
- Research papers of the week – January 15, 2024
- Research papers of the week – January 8, 2024
- Research papers of the week – January 1, 2024
- Research papers of the week – December 25, 2023
- Research papers of the week – December 18, 2023
- Research papers of the week – December 11, 2023
- Research papers of the week – December 4, 2023
- Research papers of the week – November 27, 2023
- Research papers of the week – November 20, 2023
- Research papers of the week – November 13, 2023
- Research papers of the week – November 6, 2023
- Research papers of the week – October 30, 2023
- Research papers of the week – October 23, 2023
- Research papers of the week – October 16, 2023
- Research papers of the week – October 9, 2023
- Research papers of the week – October 2, 2023
- Research papers of the week – September 25, 2023
- Research papers of the week – September 18, 2023
- Research papers of the week – September 11, 2023
- Research papers of the week – September 4, 2023
- Research papers of the week – August 28, 2023
- Research papers of the week – August 21, 2023
- Research papers of the week – August 14, 2023
- Research papers of the week – August 7, 2023
- Research papers of the week – July 31, 2023
- Research papers of the week – July 24, 2023
- Research papers of the week – July 17, 2023
- Research papers of the week – July 10, 2023
- Research papers of the week – July 3, 2023
- Research papers of the week – June 26, 2023
- Research papers of the week – June 19, 2023
- Research papers of the week – June 12, 2023
- Research papers of the week – June 5, 2023
- Research papers of the week – May 29, 2023
- Research papers of the week – May 22, 2023
- Research papers of the week – May 15, 2023
- Research papers of the week – May 8, 2023
- Research papers of the week – May 4, 2023
- Research papers of the week – April 24, 2023
- Research papers of the week – April 17, 2023
- Research papers of the week – April 11, 2023
- Research papers of the week – April 3, 2023
- Research papers of the week – March 27, 2023
- Research papers of the week – March 20, 2023
- Research papers of the week – March 13, 2023
- Research papers of the week – March 6, 2023
- Research papers of the week – February 27, 2023
- Research papers of the week – February 20, 2023
- Research papers of the week – February 13, 2023
- Research papers of the week – February 6, 2023
- Research papers of the week – January 30, 2023
- Research papers of the week – January 23, 2023
- Research papers of the week – January 16, 2023
- Research papers of the week – January 9, 2023
- Research papers of the week – January 2, 2023
- Research papers of the week – December 26, 2022
- Research papers of the week – December 19, 2022
- Research papers of the week – December 12, 2022
- Research papers of the week – December 5, 2022
- Research papers of the week – November 28, 2022
- Research papers of the week – November 21, 2022
- Research papers of the week – November 14, 2022
- Research papers of the week – November 7, 2022
- Research papers of the week – October 31, 2022
- Research papers of the week – October 24, 2022
- Research papers of the week – October 17, 2022
- Research papers of the week – October 3, 2022
- Research papers of the week – September 26, 2022
- Research papers of the week – September 20, 2022
- Research papers of the week – September 12, 2022
- Research papers of the week – September 5, 2022
- Research papers of the week – August 29, 2022
- Research papers of the week – August 22, 2022
- Research papers of the week – August 15, 2022
- Research papers of the week – August 8, 2022
- Research papers of the week – August 1, 2022
- Research papers of the week - July 25, 2022
- Research papers of the week - July 18, 2022
- Research papers of the week - July 11, 2022
- Research papers of the week - July 4, 2022
- Research papers of the week - June 27, 2022
- Research papers of the week - June 20, 2022
- Research papers of the week - June 13, 2022
- Research papers of the week - June 6, 2022
- Research papers of the week - May 30, 2022
- Research papers of the week – May 22, 2022
- Research papers of the week - May 16, 2022
- Research papers of the week - May 9, 2022
- Research papers of the week - May, 4 2022
- Research papers of the week – April, 25 2022
- Research papers of the week – April 18, 2022
- Research papers of the week – April 11, 2022
- Research papers of the week – April 4, 2022
- Research papers of the week - March 28, 2022
- Research papers of the week - March 21 , 2022
- Research papers of the week - March 14, 2021
- Research papers of the week - March 7th, 2022
- Research papers of the week - Feburary 28, 2022
- Research papers of the week - Feburary 21, 2022
- Research papers of the week - Feburary 14, 2022
- Research papers of the week - Feburary 6, 2022
- Research papers of the week - January 31, 2022
- Research papers of the week – January 24, 2022
- Research papers of the week – January 17, 2022
- Research papers of the week – January 10, 2022
- Research papers of the week – January 03, 2022
- Research papers of the week – December 27, 2021
- Research papers of the week – December 20, 2021
- Research papers of the week – December 13, 2021
- Research papers of the week – December 6, 2021
- Research papers of the week – November 29, 2021
- Research papers of the week – November 22, 2021
- Research papers of the week – November 16, 2021
- Research papers of the week – November 9, 2021
- Research papers of the week – November 2, 2021
- Research papers of the week – October 25, 2021
- Research papers of the week – October 18, 2021
- Research papers of the week – October 11, 2021
- Research papers of the week – October 4, 2021
- Research papers of the week – September 27, 2021
- Research papers of the week – September 20, 2021
- Research papers of the week – September 13, 2021
- Research papers of the week – September 6, 2021
- Research papers of the week – August 30, 2021
- Research papers of the week – August 23, 2021
- Research papers of the week – August 16, 2021
- Research papers of the week – August 9, 2021
- Research papers of the week – August 2, 2021
- Research papers of the week – July 26, 2021
- Research papers of the week – July 19, 2021
- Research papers of the week – July 12, 2021
- Research papers of the week – July 5, 2021
- Research papers of the week – June 28, 2021
- Research papers of the week – June 14, 2021
- Research papers of the week – June 7, 2021
- Research papers of the week – May 31, 2021
- Research papers of the week – May 24, 2021
- Research papers of the week – May 17, 2021
- Research papers of the week – May 10, 2021
- Research papers of the week – May 3, 2021
- Research papers of the week – April 26, 2021
- Research papers of the week – April 19, 2021
- Research papers of the week – April 12, 2021
- Research papers of the week – April 5, 2021
- Research papers of the week – March 29, 2021
- Research papers of the week – March 22, 2021
- Research papers of the week – March 15, 2021
- Research papers of the week – March 8, 2021
- Research papers of the week – March 1, 2021
- Research papers of the week – February 22, 2021
- Research papers of the week – February 15, 2021
- Research papers of the week – February 8, 2021
- Research papers of the week – February 1, 2021
- Research papers of the week – January 25, 2021
- Research papers of the week – January 18, 2021
- Research papers of the week – January 11, 2021
- Research papers of the week – January 4, 2021
- Research papers of the week – December 21, 2020
- Research papers of the week – December 14, 2020
- Research papers of the week – December 7, 2020
- Research papers of the week – November 30, 2020
- Research papers of the week – November 23, 2020
- Research papers of the week – November 16, 2020
- Research papers of the week – November 9, 2020
- Research papers of the week – November 2, 2020
- Research papers of the week – October 26, 2020
- Research papers of the week – October 19, 2020
- Research papers of the week – October 12, 2020
- Research papers of the week – October 5, 2020
- Research papers of the week – September 28, 2020
- UPWr Doctoral School
- Research collaboration offers
- Post-doc offer
- Offers for UA reseachers
- Offers for UA reseachers – Leading Research Groups (UPWr)
- Innovative diagnostics and veterinary therapy – Inno-WET
- Agriculture-Environment-Natural Resources – AgrEn
- Biotechnology for life and industry – BioTech@Life
- Biocatalysis and biological activity – BioActiv
- Reg-Med-Lab – Marycz Lab
- Sustainable Cities and Regions – SCR
- Space And Close Earth Observation Sciences – SpaceOS
- General veterinary, preclinical and hygienic science – WET-PPH
- Waste and Biomass Valorization Group – WBVG
- Offers for UA researchers outside of UPWr
- Programmes and Grants
- Offers for UA reseachers – Leading Research Groups (UPWr)
- The Excellence Initiative – Research University
- European Charter for Researchers
- Collaboration
- Admission
- For employees