Best microbiological experimental work
A team led by Professor Maciej Ugorski was recognized by the Microbiology Committee of Polish Academy of Sciences for the best experimental work in the category of microbiology FimH protein of type 1 fimbriae in adhesion of Salmonella Enteritidis and Salmonella Typhimurium into host cells and tissues.
The research was carried out by Professor Maciej Ugorski and his team of doctoral students: Krzysztof Grzymajło, Marta Kuźmińska – Bajor and Jakub Jaworski from Department of Biochemistry, Pharmacology and Toxicology of Veterinary Medicine Faculty of Wrocław University of Environmental and Life Sciences and Professor Piotr Dobryszycki from the Department of Biochemistry and Biotechnology of Chemistry Department of Wrocław University of Technology. This work, which is a continuation of earlier studies, improves the understanding of the molecular basis of adhesion processes as it relates to the recognition and the binding of the Salmonella into host cells. In addition to cognitive aspects, the results may be important for developing new strategies in the prevention and treatment of infections caused by these pathogens in humans and animals. The article "The high-adhesive properties of the FimH adhesion of Salmonella enterica serovar Enteritidis are determined to single F118S substitution" was published in 2010 in the July issue of the journal Microbiology - Society for General Microbiology (SGM).
